“Big Bang” theory

One of the most known comedies is the so-called “Big Bang” theory.  This theory is the most widely accepted, coming from the famous scientist Einstein. All the comedy tricks are based on the scientific work of a group of young scientists, along with their personal characteristics.

The show originally centered on five characters living in Pasadena, California:  Leonard Hofstadter  and   Sheldon Cooper, both physicists at Caltech, who share an apartment; Penny, a waitress and aspiring actress who lives across the hall; and Leonard and Sheldon's similarly geeky and socially awkward friends and co-workers, aerospace engineer Howard Wolowitz and astrophysicist Raj Koothrappali. Over time, supporting characters have been promoted to starring roles including, physicist Leslie Winkle, neuroscientist  Amy Farrah  Fowler,  microbiologist Bernadette Rostenkowski, and Stuart Bloom, the cash-strapped owner of the comic book store the characters often visit. As the theme of the show revolves around science, many distinguished and high-profile scientists have appeared as guest stars on the show.

            Famous astrophysicist and Nobel laureate George Smoot had a short appearance in the second season. Theoretical physicist Brian Greene appeared in the fourth season, as well as astrophysicist, science populizer, and physics outreach specialist Neil deGrasse Tyson, who also appeared in the twelfth season.

Cosmologist Stephen Hawking made a short guest appearance in the fifth-season episode;^[57] in the eighth season, Hawking video conferences with Sheldon and Leonard, and makes another appearance in the 200th episode. In the fifth and sixth seasons, NASA astronaut Michael J. Massimino played himself multiple times in the role of Howard's fellow astronaut. Bill Nye appeared in the seventh and twelfth seasons.

I believe that this comedy show is the funniest TV series. It is suitable for all ages, very clever and many people all over the world watch it phanatically.